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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
MAPK15
All Species:
16.97
Human Site:
Y340
Identified Species:
37.33
UniProt:
Q8TD08
Number Species:
10
Phosphosite Substitution
Charge Score:
-0.3
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q8TD08
NP_620590.2
544
59832
Y340
P
E
Y
R
S
R
V
Y
Q
M
I
L
E
C
G
Chimpanzee
Pan troglodytes
Rhesus Macaque
Macaca mulatta
Dog
Lupus familis
XP_539201
559
60934
R347
V
Y
Q
M
I
L
E
R
R
G
D
G
R
V
P
Cat
Felis silvestris
Mouse
Mus musculus
Q80Y86
549
60660
Y341
P
E
Y
R
K
R
L
Y
Q
I
I
L
E
Q
S
Rat
Rattus norvegicus
Q9Z2A6
547
60705
Y341
P
E
Y
R
N
R
L
Y
Q
M
I
L
E
R
R
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
XP_423954
600
66936
Y365
A
E
Y
R
N
K
L
Y
E
M
I
L
E
K
K
Frog
Xenopus laevis
P26696
361
41238
T184
A
D
P
D
H
D
H
T
G
F
L
T
E
Y
V
Zebra Danio
Brachydanio rerio
NP_001018581
524
58806
Y341
T
Q
Y
R
N
K
L
Y
E
M
I
V
E
K
R
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
XP_392445
747
85295
V424
Y
E
P
S
Y
V
E
V
R
S
Q
L
P
N
K
Nematode Worm
Caenorhab. elegans
Q11179
470
54020
K293
L
L
I
F
A
P
Q
K
R
L
T
V
E
Q
C
Sea Urchin
Strong. purpuratus
XP_001203135
583
64666
R352
K
E
K
K
A
R
H
R
Q
Q
L
R
E
A
Q
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
P14681
368
42674
Y191
E
Y
V
A
T
R
W
Y
R
A
P
E
I
M
L
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
N.A.
N.A.
71.5
N.A.
69.2
68.7
N.A.
N.A.
45.3
28.6
48.3
N.A.
N.A.
34.6
42.6
44.9
Protein Similarity:
100
N.A.
N.A.
77.8
N.A.
75.5
75.1
N.A.
N.A.
60
42
64.8
N.A.
N.A.
50.5
61.2
62.6
P-Site Identity:
100
N.A.
N.A.
0
N.A.
66.6
73.3
N.A.
N.A.
53.3
6.6
40
N.A.
N.A.
13.3
6.6
26.6
P-Site Similarity:
100
N.A.
N.A.
6.6
N.A.
80
86.6
N.A.
N.A.
80
20
80
N.A.
N.A.
20
33.3
46.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
29.7
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
42.8
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
13.3
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
26.6
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
19
0
0
10
19
0
0
0
0
10
0
0
0
10
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
10
10
% C
% Asp:
0
10
0
10
0
10
0
0
0
0
10
0
0
0
0
% D
% Glu:
10
55
0
0
0
0
19
0
19
0
0
10
73
0
0
% E
% Phe:
0
0
0
10
0
0
0
0
0
10
0
0
0
0
0
% F
% Gly:
0
0
0
0
0
0
0
0
10
10
0
10
0
0
10
% G
% His:
0
0
0
0
10
0
19
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
10
0
10
0
0
0
0
10
46
0
10
0
0
% I
% Lys:
10
0
10
10
10
19
0
10
0
0
0
0
0
19
19
% K
% Leu:
10
10
0
0
0
10
37
0
0
10
19
46
0
0
10
% L
% Met:
0
0
0
10
0
0
0
0
0
37
0
0
0
10
0
% M
% Asn:
0
0
0
0
28
0
0
0
0
0
0
0
0
10
0
% N
% Pro:
28
0
19
0
0
10
0
0
0
0
10
0
10
0
10
% P
% Gln:
0
10
10
0
0
0
10
0
37
10
10
0
0
19
10
% Q
% Arg:
0
0
0
46
0
46
0
19
37
0
0
10
10
10
19
% R
% Ser:
0
0
0
10
10
0
0
0
0
10
0
0
0
0
10
% S
% Thr:
10
0
0
0
10
0
0
10
0
0
10
10
0
0
0
% T
% Val:
10
0
10
0
0
10
10
10
0
0
0
19
0
10
10
% V
% Trp:
0
0
0
0
0
0
10
0
0
0
0
0
0
0
0
% W
% Tyr:
10
19
46
0
10
0
0
55
0
0
0
0
0
10
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _